Amongst 67 lacunar and 67 mild cortical strokes, mean age 64 and 67 years, respectively, we found no difference in MCA mean flow velocity between cortical and lacunar patients.
Increasing age and white matter lesion scores were independently associated with lower MCA flow velocities (0.2 cms fall in flow velocity per point increase in white matter lesion score, p = 0.004). MCA atheromatous stenosis is unlikely to be a common cause of lacunar stroke in white populations.
Many of the CNS changes observed in diabetic patients and animal models of diabetes are reminiscent of the changes seen in normal aging.
The central commonalities between diabetes-induced and age-related CNS changes have led to the theory of advanced brain aging in diabetic patients.
Lacunar infarcts were defined as acute ischaemic lesions (as above), rounded, of , with turbulence/spectral broadening, /– vessel wall vibration . If your browser does not accept cookies, you cannot view this site.There are many reasons why a cookie could not be set correctly.There is now evidence illustrating that both T1D and T2D can also cause complications within the central nervous system (CNS).Manifestations of diabetes-induced CNS complications may include structural alterations or brain atrophy, as well as changes in electrophysiological properties that ultimately result in deficits in cognitive performance .This review summarizes the findings of the literature as they relate to the relationship between diabetes and dementia and discusses some of the potential contributors to diabetes-induced CNS impairments.Diabetes mellitus is an endocrine disorder of carbohydrate metabolism resulting from inadequate insulin release (insulin-dependent diabetes mellitus, or type 1 diabetes; T1D) or insulin insensitivity (non-insulin-dependent diabetes mellitus, or type 2 diabetes; T2D), both of which result in hyperglycemia if uncontrolled.This site stores nothing other than an automatically generated session ID in the cookie; no other information is captured.In general, only the information that you provide, or the choices you make while visiting a web site, can be stored in a cookie.Central nervous system (CNS) complications resulting from diabetes is a problem that is gaining more acceptance and attention.Recent evidence suggests morphological, electrophysiological and cognitive changes, often observed in the hippocampus, in diabetic individuals.